Data-Driven Trial Rescue

Every day a struggling trial goes unnoticed, CROs lose revenue and sponsors lose millions. But not every trial can be saved—the key is knowing which ones can be rescued and when to act. Yet, identifying at-risk trials remains a slow, manual process, causing missed intervention opportunities and trial failures. Without real-time visibility, enrollment declines, protocol delays, and execution failures quickly spiral out of control, making recovery nearly impossible.

Waiting too long to act comes at a steep price. Delays beyond 150 days increase the likelihood of trial termination by 41%, while enrollment drops of 75% or more double the risk of early failure. In fact, 55% of failed trials cite low enrollment as the primary reason for termination. Without early intervention, these issues compound, making recovery increasingly difficult. AppliedXL eliminates the guesswork by automatically detecting trials at risk of delays, failure, or recruitment struggles—empowering CRO BD teams to engage sponsors early and position their services as the solution before setbacks become irreversible.

How AppliedXL Helps CROs Rescue Trials at the Right Moment

Step 1: Detecting Risk Before It Escalates
AppliedXL continuously monitors clinical trials, identifying delays, failures, and recruitment struggles before they become critical. By surfacing these risks early, CROs can act at the right moment—connecting with sponsors before problems spiral out of control.

Step 2: AI-Powered Risk Detection & Precision Timing
Timing is everything. If CROs engage too early, sponsors may not be ready. Too late, and key decisions have already been made. AppliedXL’s AI pinpoints when intervention will have maximum impact by detecting subtle shifts in trial activity—such as slowing recruitment, execution failures, or protocol amendments—ensuring outreach happens at the precise moment when sponsors are most likely to engage.

Beyond individual trials, AppliedXL uncovers broader patterns that expose systemic inefficiencies, including sponsors with repeated delays, clinical stages plagued by setbacks, and hidden bottlenecks where CROs can become indispensable partners.

Step 3: Real-Time, Precision Reports for CROs

AppliedXL transforms trial monitoring from a slow, manual process into a real-time competitive advantage. By automating risk detection and delivering proactive alerts, CROs can engage sponsors before issues even surface. It eliminates manual tracking, allowing CROs to identify at-risk trials first. The system automates risk detection, pinpointing sponsors who need intervention at the right moment. Real-time alerts ensure CROs take action before sponsors even recognize the problem, maximizing contract conversions and securing engagements at the optimal time.

The result? Faster interventions, more successful trials, and higher revenue. With AppliedXL, CROs no longer react to problems—they prevent them.